Intracranial tumor in children: MR imaging findings within 24 hours of craniotomy. Radiology 1997 Dec;205(3):807-12
Date
12/11/1997Pubmed ID
9393539DOI
10.1148/radiology.205.3.9393539Scopus ID
2-s2.0-0030667070 (requires institutional sign-in at Scopus site) 41 CitationsAbstract
PURPOSE: To evaluate whether very early magnetic resonance (MR) imaging enables distinction of residual tumor from benign postoperative change in children.
MATERIALS AND METHODS: Forty-six postoperative MR examinations were performed in 43 children with intracranial tumors within 24 hours of the completion of surgery during a 2-year period. These examinations were categorized according to whether residual tumor could be definitely identified or excluded, or whether the diagnosis was uncertain.
RESULTS: Contrast enhancement occurred in 33 of 46 MR examinations performed within 24 hours of surgery. In 18 instances, this was associated with obvious residual tumor. In 15 patients, only small amounts of linear or patchy enhancement were seen. Of these, seven patients (46%) were disease-free for an average of 4.5 years. Assessment for postoperative enhancement was hampered in seven patients because of the presence of methemoglobin in the tumor bed. Contrast enhancement was not observed in two patients before surgery.
CONCLUSION: Surgically induced, MR-detectable contrast enhancement and extracellular methemoglobin formation occurs within 24 hours of the completion of intracranial surgery. This can interfere with the detection of small amounts of residual tumor.
Author List
Oser AB, Moran CJ, Kaufman BA, Park TSAuthor
Bruce A. Kaufman MD Adjunct Professor in the Neurosurgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
BrainBrain Neoplasms
Child
Contrast Media
Craniotomy
Female
Gadolinium DTPA
Humans
Magnetic Resonance Imaging
Male
Methemoglobin
Neoplasm, Residual
Postoperative Period
Prospective Studies
Time Factors
