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Evidence for using chlorhexidine gluconate preoperative cleansing to reduce the risk of surgical site infection. AORN J 2010 Nov;92(5):509-18



Pubmed ID




Scopus ID

2-s2.0-78049241602   59 Citations


Surgical site infections are associated with significant patient morbidity and mortality and are the third most frequently reported health care-associated infection. A suggested risk reduction strategy has been the preadmission shower or skin cleansing with chlorhexidine gluconate (CHG). Although older clinical trials question the clinical efficacy of cleansing with CHG, recent evidence-based scientific and clinical studies support two types of CHG application (ie, a 2% CHG-coated cloth or 4% CHG soap) using a standardized, timed process before hospital admission as an effective strategy for reducing the risk of postoperative surgical site infection.

Author List

Edmiston CE Jr, Okoli O, Graham MB, Sinski S, Seabrook GR


Mary Beth Graham MD Associate Chief, Professor in the Medicine department at Medical College of Wisconsin
Gary R. Seabrook MD Chief, Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Anti-Infective Agents, Local
Evidence-Based Medicine
Preoperative Care
Risk Factors
Safety Management
Surgical Wound Infection
Treatment Outcome
jenkins-FCD Prod-468 69a93cef3257f26b866d455c1d2b2d0f28382f14