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A new noninvasive method for determination of laryngeal sensory function. Laryngoscope 2011 Jan;121(1):158-63



Pubmed ID




Scopus ID

2-s2.0-78651107070   8 Citations


OBJECTIVES/HYPOTHESIS: We report a new surface technique for studying sensory conduction in the superior laryngeal nerve (SLN).

STUDY DESIGN: Prospective controlled cohort study at an academic tertiary care hospital.

METHODS: Surface stimulation of the vagus nerve 7-10 cm proximal to a surface electrode placed over the cricothyroid muscle was performed in controls and in subjects with needle electromyographic-confirmed laryngeal neuropathy. Cathodal stimulation was applied below the mastoid process behind the sternocleidomastoid muscle. Nerve conduction parameters were determined.

RESULTS: Noninvasive SLN evoked potential studies were performed on healthy volunteers (n = 28) as well as neuropathic subjects (n = 27). Compared to controls, the neuropathic subjects had statistically significant differences in baseline-to-peak amplitude, conduction velocity, and intrasubject side-to-side amplitude ratio (P <.01) of their surface evoked laryngeal sensory action potential (SELSAP).

CONCLUSIONS: Laryngeal sensory nerve conduction can be determined noninvasively by evaluating SELSAP waveform. This study provides a reproducible method for electrophysiologic evaluation of a sensory branch of the SLN.

Author List

Bock JM, Blumin JH, Toohill RJ, Merati AL, Prieto TE, Jaradeh SS


Joel H. Blumin MD Chief, Professor in the Otolaryngology department at Medical College of Wisconsin
Jonathan Bock MD Associate Professor in the Otolaryngology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Action Potentials
Cranial Nerve Diseases
Electric Stimulation
Evoked Potentials
Laryngeal Nerves
Middle Aged
Neural Conduction
Neurologic Examination
Reaction Time
Vagus Nerve
jenkins-FCD Prod-467 7c8a156729bba74d775d9c546792cde315827259