Faculty Collaboration Database

Lower body negative pressure: a test of cardiovascular autonomic function. Muscle Nerve 2001 Apr;24(4):481-7

Date

03/27/2001

Pubmed ID

11268019

DOI

10.1002/mus.1030

Scopus ID

2-s2.0-0035085961 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

Lower body negative pressure (LBNP) may provide an alternative test of cardiovascular autonomic function for patients unable to perform the Valsalva maneuver (VM). LBNP at -40 mmHg for 30 s was compared to the VM at 40 mmHg for 15 s with heart rate and blood pressure measured continuously in three age groups: 10-25 years; 26-40 years; and 41-55 years. Heart rate and blood pressure responses were comparable, with moderately diminished changes in blood pressure and heart rate in the LBNP test. When heart response to LBNP was converted to a ratio similar to that calculated for the VM, a high degree of correlation was found (R(2) = 0.5711). The LBNP test shows promise as an alternative test of cardiovascular autonomic function based on studies in normal subjects. The less marked changes may relate to the more passive nature of the applied stress. Future work should improve the device's accessibility and establish values for patients with autonomic disorders.

Author List

Patel AR, Engstrom JE, Tusing LD, McNeeley KJ, Chelimsky TC

MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Autonomic Nervous System
Blood Pressure
Cardiovascular System
Child
Female
Heart Rate
Humans
Lower Body Negative Pressure
Male
Middle Aged
Reference Values
Valsalva Maneuver