Racial differences in coronary artery calcification in older adults. Arterioscler Thromb Vasc Biol 2002 Mar 01;22(3):424-30
Date
03/09/2002Pubmed ID
11884285DOI
10.1161/hq0302.105357Scopus ID
2-s2.0-0036118446 (requires institutional sign-in at Scopus site) 109 CitationsAbstract
Reports on race-related differences in coronary artery calcium (CAC) are just beginning to emerge and have not been well studied in the elderly. This study was undertaken to assess whether such differences exist and the relationship between CAC and cardiovascular risk factors in a cohort of elderly community-dwelling adults. CAC was measured by using electron-beam tomography in 614 adults (aged 67 to 99 years), of whom 59% were women and 23% were black. The median CAC score was lower in blacks than in whites for men (159 versus 787, respectively; P<0.001) and for women (134 versus 233, respectively; P=0.02) after adjustment for age, cardiovascular disease, and risk factors for cardiovascular disease, although this difference was stronger and remained significant among men only. Lower CAC scores were also observed in the subgroup of blacks with a history of myocardial infarction. The lower CAC scores in blacks compared with whites observed in this study is consistent with either a lower prevalence of coronary artery disease or a lower extent of calcification of coronary artery disease.
Author List
Newman AB, Naydeck BL, Whittle J, Sutton-Tyrrell K, Edmundowicz D, Kuller LHAuthor
Jeffrey Whittle MD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Age FactorsAged
Calcinosis
Cohort Studies
Coronary Artery Disease
Female
Humans
Logistic Models
Male
Risk Factors
Sex Factors
Tomography, X-Ray Computed
