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Craniosynostosis following hemispherectomy in a 2.5-month-old boy with intractable epilepsy. J Neurosurg Pediatr 2011 Nov;8(5):450-4 PMID: 22044367

Pubmed ID

22044367

DOI

10.3171/2011.8.PEDS11176

Abstract

The authors report on the case of a 6-week-old boy who presented with infantile spasms. At 2.5 months of age, the patient underwent a right hemispherectomy. Approximately 3 months postoperatively, the patient presented with left coronal craniosynostosis. Subsequent cranial vault remodeling resulted in satisfactory cosmesis. Four years after surgery, the patient remains seizure free without the need for anticonvulsant medications. The authors believe this to be the first reported case of iatrogenic craniosynostosis due to hemispherectomy, and they describe 2 potential mechanisms for its development. This case suggests that, in the surgical treatment of infants with intractable epilepsy, minimization of brain volume loss through disconnection techniques should be considered, among other factors, when determining the best course of action.

Author List

Jazayeri MA, Jensen JN, Lew SM

Authors

John N. Jensen MD Associate Professor in the Plastic Surgery department at Medical College of Wisconsin
Sean Lew MD Chief, Professor in the Neurosurgery department at Medical College of Wisconsin




Scopus

2-s2.0-80655147984   1 Citations

MESH terms used to index this publication - Major topics in bold

Adrenocorticotropic Hormone
Anticonvulsants
Clonazepam
Craniosynostoses
Craniotomy
Electroencephalography
Epilepsy
Fructose
Hemispherectomy
Humans
Infant
Male
Postoperative Complications
Spasms, Infantile
Tomography, X-Ray Computed
jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad