Medical College of Wisconsin
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Detection of primary lung tumors in rodents by magnetic resonance imaging. Cancer Res 2004 Apr 15;64(8):2740-2



Pubmed ID




Scopus ID

2-s2.0-9244262630   40 Citations


This report describes recent efforts to develop and apply small animal magnetic resonance imaging methods to the study of lung tumors in mice. Magnetic resonance (MR) images obtained with respiratory gating, with data collection synchronized with the respiration of the animal, allow visualization of submillimeter tumors in animals treated with a lung carcinogen. Comparison of the MR images with gross pathology of these lungs demonstrates the utility of the imaging methods for measuring tumor burden. As a noninvasive imaging modality that uses nonionizing radiation, MR is well suited to longitudinal studies aimed at understanding the factors that control the onset and development of lung tumors and their response to therapy in a wide variety of animal models.

Author List

Garbow JR, Zhang Z, You M


Ming You MD, PhD Associate Provost, Professor in the Pharmacology and Toxicology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Lung Neoplasms
Magnetic Resonance Imaging
Mice, Inbred A
Mice, Transgenic
jenkins-FCD Prod-409 d1e206b0be345926047b0d9c353c78a4cce4058b