Enterobacter cloacae bacteremia in children: a review of 30 cases in 12 years. Clin Pediatr (Phila) 1991 May;30(5):310-3
Date
05/01/1991Pubmed ID
2044341DOI
10.1177/000992289103000509Scopus ID
2-s2.0-0025907368 (requires institutional sign-in at Scopus site) 21 CitationsAbstract
A review was performed of the 30 cases of pediatric Enterobacter cloacae (EBC) bacteremia which occurred at our institution during a 12-year period. These 30 cases represented 88% of all cases in which EBC was isolated by blood culture (four other instances were considered contaminants); the rate of isolation of this organism relative to all positive blood cultures was 0.6%. There were 14 patients less than 12 months of age, with 10 less than 2 months of age. Infection was nosocomially-acquired in 17 cases. At the time the positive blood culture was obtained, 5 patients were afebrile, and 8 patients (five immunocompromised) had been receiving parenteral antibiotic therapy to which the organism exhibited in-vitro sensitivity for at least 24 hours. EBC was a constituent of polymicrobial bacteremia in 6 cases; in 5 instances the associated organisms were also gram-negative bacteria. There were a total of 33 underlying medical conditions or foci of infection associated with EBC bacteremia identified in 27 patients, the most common of which were immune-deficiency state (17) and gastrointestinal tract lesions (6). There were 3 patients who died. EBC bacteremia is a relatively rare pediatric infection. It is commonly nosocomially-acquired, and afflicts children who are younger-aged or compromised by underlying medical problems.
Author List
Bonadio WA, Margolis D, Tovar MAuthor
David A. Margolis MD Chair, Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Anti-Bacterial AgentsChild, Preschool
Cross Infection
Enterobacter
Enterobacteriaceae Infections
Female
Humans
Infant
Infant, Newborn
Male
Microbial Sensitivity Tests
Prognosis
Sepsis
