Radium in Wisconsin drinking water: an analysis of osteosarcoma risk. Arch Environ Health 2002;57(4):294-303
Date
01/18/2003Pubmed ID
12530595DOI
10.1080/00039890209601412Scopus ID
2-s2.0-0036664565 (requires institutional sign-in at Scopus site) 16 CitationsAbstract
Epidemiological studies of radium dial painters have found an association between exposure to high-dose radium and bone cancers. However, only limited data exist on the relationship between low doses of radium, as are found in some drinking water sources, and osteosarcoma. The authors conducted a population-based case-control study to examine the association between exposure to radium in drinking water and the occurrence of osteosarcoma. Estimates of radium exposure and covariates used were based on subjects' residential ZIP codes. The median radium level was not significantly associated with osteosarcoma (odds ratio = .98; 95% confidence interval = .93, 1.04; p = .56). The authors found no evidence that radium, at current levels in Wisconsin drinking water, resulted in excess cases of osteosarcoma.
Author List
Guse CE, Marbella AM, George V, Layde PMMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Aged
Bone Neoplasms
Case-Control Studies
Child
Child, Preschool
Female
Humans
Infant
Infant, Newborn
Male
Middle Aged
Odds Ratio
Osteosarcoma
Radium
Registries
Risk Assessment
Water Supply
Wisconsin