Medical College of Wisconsin
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Health-related quality of life in sickle cell disease: past, present, and future. Pediatr Blood Cancer 2012 Aug;59(2):377-85 PMID: 22522407

Pubmed ID





Health-related quality of life (HRQL) is defined as the patient's appraisal of how his/her well being and level of functioning, compared to the perceived ideal, are affected by individual health. The study of HRQL in children and adults with sickle cell disease (SCD) has begun to flourish. Given the devastating complications of the disease and other co-morbid factors patients experience that influence HRQL, it is increasingly important to understand HRQL. The focus of this critical review was to examine past and current research in HRQL in SCD where a validated instrument was used. In addition, future directions for HRQL in SCD are explored.

Author List

Panepinto JA, Bonner M


Julie A. Panepinto MD, MSPH Professor in the Pediatrics department at Medical College of Wisconsin


2-s2.0-84862269475   55 Citations

MESH terms used to index this publication - Major topics in bold

Anemia, Sickle Cell
Health Status
Quality of Life
jenkins-FCD Prod-336 69ef4a6b262d135130251597d5d39873903802b5