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A perspective on the selection of unrelated donors and cord blood units for transplantation. Blood 2012 Jul 12;120(2):259-65 PMID: 22596257 PMCID: PMC3398760

Pubmed ID

22596257

Abstract

Selection of a suitable graft for allogeneic hematopoietic stem cell transplantation involves consideration of both donor and recipient characteristics. Of primary importance is sufficient donor-recipient HLA matching to ensure engraftment and acceptable rates of GVHD. In this Perspective, the National Marrow Donor Program and the Center for International Blood and Marrow Transplant Research provide guidelines, based on large studies correlating graft characteristics with clinical transplantation outcomes, on appropriate typing strategies and matching criteria for unrelated adult donor and cord blood graft selection.

Author List

Spellman SR, Eapen M, Logan BR, Mueller C, Rubinstein P, Setterholm MI, Woolfrey AE, Horowitz MM, Confer DL, Hurley CK, National Marrow Donor Program, Center for International Blood and Marrow Transplant Research

Authors

Mary Eapen MBBS, DCh, MRCPI, MS Professor in the Medicine department at Medical College of Wisconsin
Mary M. Horowitz MD, MS Center Director, Professor in the Medicine department at Medical College of Wisconsin
Brent R. Logan PhD Director, Professor in the Institute for Health and Equity department at Medical College of Wisconsin




Scopus

2-s2.0-84864144424   95 Citations

MESH terms used to index this publication - Major topics in bold

Adult
Adult Stem Cells
Cord Blood Stem Cell Transplantation
Donor Selection
Hematopoietic Stem Cell Transplantation
Histocompatibility Testing
Humans
Infant, Newborn
Peripheral Blood Stem Cell Transplantation
Tissue Donors
Transplantation Immunology
United States
jenkins-FCD Prod-299 9ef562391eceb2b8f95265c767fbba1ce5a52fd6