Hydronephrosis: a view from the inside. Pediatr Clin North Am 2012 Aug;59(4):839-51
Date
08/04/2012Pubmed ID
22857832DOI
10.1016/j.pcl.2012.05.008Scopus ID
2-s2.0-84864412203 (requires institutional sign-in at Scopus site) 22 CitationsAbstract
Unilateral ureteropelvic junction obstruction (UPJO) is the most common prenatally detected disease leading to hydronephrosis. The obstructive anatomic lesion leads to varying degrees of hydronephrosis, ranging from no apparent effect on renal function to atrophy. Furthermore, the natural course of hydronephrosis varies from spontaneous resolution to progressive deterioration and may take upwards of 3 years for a kidney to declare itself. The objectives of this article are to update our knowledge regarding the evaluation and management of UPJO in depth and to discuss the emerging value of urinary proteome analysis to the clinical arena.
Author List
Mesrobian HG, Mirza SPMESH terms used to index this publication - Major topics in bold
BiomarkersDiagnosis, Differential
Diagnostic Imaging
Disease Progression
Early Diagnosis
Female
Humans
Hydronephrosis
Infant, Newborn
Male
Pregnancy
Prenatal Diagnosis
