Imaging retinal mosaics in the living eye. Eye (Lond) 2011 Mar;25(3):301-8
Date
03/11/2011Pubmed ID
21390064Pubmed Central ID
PMC3178316DOI
10.1038/eye.2010.221Scopus ID
2-s2.0-79952604754 (requires institutional sign-in at Scopus site) 83 CitationsAbstract
Adaptive optics imaging of cone photoreceptors has provided unique insight into the structure and function of the human visual system and has become an important tool for both basic scientists and clinicians. Recent advances in adaptive optics retinal imaging instrumentation and methodology have allowed us to expand beyond cone imaging. Multi-wavelength and fluorescence imaging methods with adaptive optics have allowed multiple retinal cell types to be imaged simultaneously. These new methods have recently revealed rod photoreceptors, retinal pigment epithelium (RPE) cells, and the smallest retinal blood vessels. Fluorescence imaging coupled with adaptive optics has been used to examine ganglion cells in living primates. Two-photon imaging combined with adaptive optics can evaluate photoreceptor function non-invasively in the living primate retina.
Author List
Rossi EA, Chung M, Dubra A, Hunter JJ, Merigan WH, Williams DRMESH terms used to index this publication - Major topics in bold
Diagnostic ImagingHumans
Optics and Photonics
Photoreceptor Cells, Vertebrate
Retina
Retinal Ganglion Cells
Retinal Pigment Epithelium
Retinal Vessels