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Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis. Pediatr Infect Dis J 2013 Feb;32(2):189-91

Date

09/28/2012

Pubmed ID

23014355

Pubmed Central ID

PMC3548939

DOI

10.1097/INF.0b013e3182748fe9

Scopus ID

2-s2.0-84873058118   2 Citations

Abstract

Hydrogen sulfide is an environmental toxicant and gaseous neurotransmitter. It is produced enterically by sulfur-reducing bacteria and invasive pathogens including Streptococcus anginosus group, Salmonella and Citrobacter. We describe putative focal hydrogen sulfide neurotoxicity after Streptococcus constellatus meningitis, treated with adjunctive sodium nitrite and hyperbaric oxygen therapy.

Author List

Verma S, Landisch R, Quirk B, Schmainda K, Prah M, Whelan HT, Willoughby RE Jr

Authors

Kathleen M. Schmainda PhD Professor in the Biophysics department at Medical College of Wisconsin
Harry T. Whelan MD Professor in the Neurology department at Medical College of Wisconsin
Rodney E. Willoughby MD Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Brain
Child, Preschool
Cognition Disorders
Dipyridamole
Humans
Hydrogen Sulfide
Hyperbaric Oxygenation
Male
Meningitis, Bacterial
Nervous System Diseases
Sodium Nitrite
Streptococcal Infections
Streptococcus anginosus
jenkins-FCD Prod-398 336d56a365602aa89dcc112f077233607d6a5abc