Use it or lose it: environmental enrichment as a means to promote successful cognitive aging. ScientificWorldJournal 2010 Jun 16;10:1129-41
Date
06/22/2010Pubmed ID
20563536Pubmed Central ID
PMC4462190DOI
10.1100/tsw.2010.111Scopus ID
2-s2.0-77955906952 (requires institutional sign-in at Scopus site) 38 CitationsAbstract
Environmental enrichment has become increasingly utilized in rodent models of aging and neurodegenerative disease in order to prevent or reverse cognitive decline and neuronal dysfunction. However, the potential application of this body of work to human cognitive aging has rarely been discussed. The present article provides an overview of the rodent research that has tested the effects of environmental enrichment on hippocampal and neocortical function, and the types of memories mediated by these brain regions. Although data from models of neurodegenerative disease are presented, primary emphasis is given to studies of aging rodents and to methodological issues (e.g., age, treatment duration, treatment type) central to the mnemonic effectiveness of enrichment treatment. The implications of this work for human cognitive aging are discussed.
Author List
Frick KM, Benoit JDAuthor
Karyn Frick BA,MA,PhD Professor in the Psychology department at University of Wisconsin - MilwaukeeMESH terms used to index this publication - Major topics in bold
AgingAnimals
Cognition
Female
Humans
Male
