Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Acute treatment of migraine and the role of triptans. Curr Neurol Neurosci Rep 2001 Mar;1(2):125-32 PMID: 11898508

Pubmed ID

11898508

Abstract

The use of triptans has improved the ability to treat migraine successfully compared with older treatments. Speed of relief, consistency of effect, and good tolerability have been the hallmarks of these agents. All of the currently available triptans have comparable efficacy and tolerability. Variables between the agents may lead to one agent or dose form being preferred over another in various clinical scenarios. The triptans that are forthcoming may improve on these options through enhanced efficacy rates, tolerability, and headache recurrence rates. There exist increasing options for migraine treatment that may further improve the clinical effects of the older and newer triptans through early treatment of migraine at the stages of mild migraine pain, or even during the prodromal phase of the attack. Additionally, recent work suggests that mini-prophylaxis of migraine at the menses is a highly successful treatment option with the triptans. In this age of managed care, providing cost-effective treatment of headache will take on increasing importance. Techniques such as stratification of acute treatments may enhance cost-effective care, whereas ready availability of the triptans may lead to significant improvements in utilization of parameters such as office visits, emergency room treatment, and even hospitalization.

Author List

Freitag FG

Author

Frederick G. Freitag DO Associate Professor in the Neurology department at Medical College of Wisconsin




Scopus

2-s2.0-0035296611   7 Citations

MESH terms used to index this publication - Major topics in bold

Acute Disease
Blood Flow Velocity
Carbazoles
Clinical Trials as Topic
Drug Administration Routes
Female
Humans
Indoles
Male
Menstruation
Migraine Disorders
Oxazolidinones
Piperidines
Practice Guidelines as Topic
Pyrrolidines
Receptor, Serotonin, 5-HT1B
Receptor, Serotonin, 5-HT1D
Receptors, Serotonin
Serotonin Receptor Agonists
Sumatriptan
Treatment Outcome
Triazoles
Tryptamines
Vasoconstriction
Vasoconstrictor Agents
jenkins-FCD Prod-300 626508253d14e4184314fb9f66322a03a5906796