Successful autologous cord blood transplantation in a child with acquired severe aplastic anemia. Pediatr Transplant 2013 May;17(3):E104-7
Date
03/08/2013Pubmed ID
23464883Pubmed Central ID
PMC4174564DOI
10.1111/petr.12068Scopus ID
2-s2.0-84876743210 (requires institutional sign-in at Scopus site) 7 CitationsAbstract
Over 400 cases of pediatric SAA occur annually in the United States. A growing number of children with SAA may have had their stem cells harvested through cord blood collection. We describe a nine-yr-old male with SAA treated successfully with an autologous cord blood transplant following immunoablative chemotherapy. With the increasing number of people cryopreserving autologous cord blood, the use of autologous cord blood in the treatment of SAA might be considered as initial therapy. This case serves to discuss approaches to preparative therapy as well as the potential complications in this growing cohort of patients.
Author List
Buchbinder D, Hsieh L, Puthenveetil G, Soni A, Stites J, Huynh V, Kirov I, Neudorf S, Rubin E, Sender L, Torno L, Margolis D, Childs R, Moore T, Nugent DAuthor
David A. Margolis MD Chair, Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Anemia, AplasticBlood Banks
Child
Cord Blood Stem Cell Transplantation
Cryopreservation
Fetal Blood
Humans
Immunosuppressive Agents
Male
Transplantation Conditioning
Transplantation, Autologous
Treatment Outcome
