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Effect of melasma on quality of life in a sample of women living in southern Brazil. J Eur Acad Dermatol Venereol 2008 Jun;22(6):655-62



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BACKGROUND: Melasma can cause a significant effect on individual emotional well-being. Melasma Quality of Life Scale (MELASQoL) is a specific questionnaire elaborated to assess the burden of melasma on patient's quality of life.

OBJECTIVE: To evaluate the clinical aspects, severity and the influence of melasma on daily living of a sample of Brazilian women.

METHODS: Cross-sectional study that enrolled 85 women with melasma older than 15 years of age. Trained investigators asked 55 questions to collect epidemiological and clinical data. The disease severity was clinically assessed using Melasma Area and Severity Index (MASI). Patients answered the Portuguese version of 10-item MELASQoL scale without coaching.

RESULTS: The mean +/- SD age was 41.1 +/- 6.8 years, and the mean +/- SD of MELASQoL score was 37.5 +/- 15.2 (median, 35). Patients with previous psychiatric diagnosis had significantly higher MELASQoL scores (mean, 42.8; SD, 13.6) than patients without this antecedent (mean, 35.4; SD, 15.4; P < 0.05). Patients with less than 8 years of school attendance also had significantly higher MELASQoL score (mean, 44; SD, 16.9) than more graduated ones (mean, 34.4; SD, 13.5; P < 0.05). The mean +/- SD MASI was 10.6 +/- 6.6 (median, 10.2). There was no correlation between MASI and MELASQoL.

CONCLUSIONS: This study confirms that MELASQoL-BP is easy to administer, adds important information about the impact of melasma on South American women's life and, finally, contributes to building evidence on the validity, reliability and cultural adaptation of the Portuguese language MELASQoL version.

Author List

Freitag FM, Cestari TF, Leopoldo LR, Paludo P, Boza JC


Frederick G. Freitag DO Professor in the Neurology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Cross-Sectional Studies
Middle Aged
Quality of Life
Surveys and Questionnaires
jenkins-FCD Prod-409 d1e206b0be345926047b0d9c353c78a4cce4058b