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Ex vivo thermoacoustic imaging over large fields of view with 108 MHz irradiation. IEEE Trans Biomed Eng 2011 Aug;58(8) PMID: 21421431

Pubmed ID

21421431

DOI

10.1109/TBME.2011.2128319

Abstract

Thermoacoustic signals are generated over a large field of view by 900 ns TE10 pulses with 108 MHz carrier frequency. Test specimens selectively absorb the TE10 pulse energy producing rapid thermal expansions that generate ultrasonic pulses. 108 MHz irradiation provides excellent depth penetration in soft tissue, allowing blood and physiologic saline to generate strong signals. Thermoacoustic signal generation from a depth of several cm is well above our systems noise floor. Rotating the test specimen provides single-slice tomographic signal encoding. Filtered back-projection reconstruction yields images over a 6.4 cm field of view. Reconstructions of tissue mimicking prostate phantoms and fresh porcine kidney tissue are presented.

Author List

Eckhart AT, Balmer RT, See WA, Patch SK

Authors

Sarah K. Patch PhD Associate Professor in the Physics department at University of Wisconsin - Milwaukee
William A. See MD Chair, Professor in the Urologic Surgery department at Medical College of Wisconsin




Scopus

2-s2.0-79960743244   18 Citations

MESH terms used to index this publication - Major topics in bold

Algorithms
Animals
Elasticity Imaging Techniques
In Vitro Techniques
Kidney
Phantoms, Imaging
Photoacoustic Techniques
Reproducibility of Results
Sensitivity and Specificity
Swine
Thermography
jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad