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Recommendations of the National Heart, Lung, and Blood Institute working group on cerebrovascular biology and disease. Stroke 2006 Jun;37(6):1578-81

Date

04/22/2006

Pubmed ID

16627792

Pubmed Central ID

PMC2730969

DOI

10.1161/01.STR.0000221297.57305.8a

Scopus ID

2-s2.0-33745141581 (requires institutional sign-in at Scopus site)   32 Citations

Abstract

The National Heart, Lung, and Blood Institute (NHLBI) convened a conference call working group, consisting of experts in stroke and cerebrovascular biology on January 28, 2005. The purpose of this working group was to develop a prioritized set of recommendations for NHLBI to establish a focused and comprehensive set of research activities in cerebrovascular biology and disease. Three thematic areas of research emerged: (1) molecular and cellular neurobiology of cerebral blood vessels, focusing on genomics and proteomics, neurovascular signaling and cerebrovascular embryogenesis, development and plasticity; (2) resource development, involving the development of new methodological approaches for normal and altered function of the neurovascular unit, collaborative research, and training in cerebrovascular pathobiology; and (3) cerebrovascular diseases and translational approaches, addressing vascular mechanisms of disease, the role of risk factors, importance of biomarkers with the ultimate goal of developing new treatments.

Author List

Iadecola C, Goldman SS, Harder DR, Heistad DD, Katusic ZS, Moskowitz MA, Simard JM, Sloan MA, Traystman RJ, Velletri PA



MESH terms used to index this publication - Major topics in bold

Animals
Biomedical Research
Blood Vessels
Cerebrovascular Circulation
Cerebrovascular Disorders
Disease Models, Animal
Genomics
Humans
Proteomics
Signal Transduction