Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association. Pediatrics 2006 Mar;117(3):959-64
Date
03/03/2006Pubmed ID
16510684DOI
10.1542/peds.2005-1683Scopus ID
2-s2.0-33645029208 (requires institutional sign-in at Scopus site) 96 CitationsAbstract
PHACE association is a rare neurocutaneous syndrome that may include posterior fossa malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, eye abnormalities, and sternal defects. The arterial abnormalities may be developmental or acquired and usually involve the cervical and cerebral vasculature. We believe that infants with PHACE association are at increased risk of arterial ischemic stroke and describe 5 infants with facial hemangiomas and structural and acquired arterial anomalies, all of whom suffered an arterial ischemic stroke during infancy.
Author List
Drolet BA, Dohil M, Golomb MR, Wells R, Murowski L, Tamburro J, Sty J, Friedlander SFMESH terms used to index this publication - Major topics in bold
Central Nervous System Vascular MalformationsEye Abnormalities
Facial Neoplasms
Female
Hemangioma
Humans
Infant
Infant, Newborn
Male
Neurocutaneous Syndromes
Stroke
Syndrome