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Hematopoietic stem cell transplantation in older persons: respecting the heterogeneity of age. Expert Rev Hematol 2014 Jun;7(3):321-4 PMID: 24785114

Pubmed ID

24785114

Abstract

Demographic trends establish that older adults are the fastest growing segment of population, with over 19% of the population expected to be aged >65 years by 2030. As the risk for hematologic malignancies increases with age, it is imperative that our field continues to strive to individualize and manage risk and benefit in an aging population. While hematologic diseases are more common in the elderly, only a small minority of patients with hematological malignancy aged >65 years receive allogeneic hematopoietic cell transplantation, relative to the burden of disease in this population. In this editorial we explore some of the obstacles to transplantation, the rationale to consider the procedure in the older adult and ways that the stem cell consultative process can be individualized. Finally, we outline key areas where additional research is needed.

Author List

Michaelis LC, Hamadani M, Hari PN

Authors

Mehdi H. Hamadani MD Professor in the Medicine department at Medical College of Wisconsin
Parameswaran Hari MD Chief, Professor in the Medicine department at Medical College of Wisconsin
Laura Michaelis MD Associate Professor in the Medicine department at Medical College of Wisconsin




Scopus

2-s2.0-84900867182   5 Citations

MESH terms used to index this publication - Major topics in bold

Age Factors
Aged
Aged, 80 and over
Female
Hematopoietic Stem Cell Transplantation
Humans
Incidence
Male
Transplantation Conditioning
jenkins-FCD Prod-299 9ef562391eceb2b8f95265c767fbba1ce5a52fd6