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Surface-evoked laryngeal sensory action potential evaluation in neurogenic chronic cough. J Voice 2014 Sep;28(5):624-30

Date

06/02/2014

Pubmed ID

24880673

DOI

10.1016/j.jvoice.2014.02.009

Scopus ID

2-s2.0-84926330985   3 Citations

Abstract

OBJECTIVES: Neurogenic chronic cough is currently a diagnosis of exclusion. We hypothesized that surface-evoked laryngeal sensory action potential (SELSAP) testing could be used to help establish a diagnosis of laryngeal sensory neuropathy as a cause of chronic cough, based on altered SELSAP waveform morphology.

STUDY DESIGN: Retrospective cohort study.

METHODS: Laryngeal electromyographic (EMG) data including SELSAP waveform testing from patients with chronic cough were directly compared with a control population without significant laryngeal symptoms, and statistical analysis of unilateral and bilateral neuropathy injury subgroups was performed.

RESULTS: Thirty patients with a chief complaint of chronic cough underwent laryngeal EMG testing since January 2000 with needle EMG and surface nerve conduction studies. SELSAP waveform analysis of unilateral and bilateral laryngeal neuropathy demonstrated significantly lowered median SELSAP peak amplitude compared with controls (P < 0.01).

CONCLUSIONS: Patients with suspected neurogenic chronic cough demonstrate statistically significant alterations in SELSAP waveform that can support a diagnosis of laryngeal sensory neuropathy.

Author List

Bock JM, Koszewski IJ, Blumin JH, Toohill RJ, Merati AL, Prieto TE, Jaradeh SS

Authors

Joel H. Blumin MD Chief, Professor in the Otolaryngology department at Medical College of Wisconsin
Jonathan Bock MD Associate Professor in the Otolaryngology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Action Potentials
Adolescent
Adult
Aged
Cough
Electromyography
Female
Follow-Up Studies
Humans
Laryngeal Diseases
Larynx
Male
Middle Aged
Retrospective Studies
Young Adult
jenkins-FCD Prod-400 0f9a74600e4e79798f8fa6f545ea115f3dd948b2