Essential requirements for setting up a stem cell processing laboratory. Bone Marrow Transplant 2014 Aug;49(8):1098-105
Date
06/17/2014Pubmed ID
24933209DOI
10.1038/bmt.2014.104Scopus ID
2-s2.0-84905692406 (requires institutional sign-in at Scopus site) 24 CitationsAbstract
The Graft Processing subcommittee of the Worldwide Network for Blood and Marrow Transplantation wrote this guideline to assist physicians and laboratory technologists with the setting up of a cell processing laboratory (CPL) to support a hematopoietic stem cell transplant program, thereby facilitating the start-up of a transplant program in a new location and improving patient access to transplantation worldwide. This guideline describes the minimal essential features of designing such a laboratory and provides a list of equipment and supply needs and staffing recommendations. It describes the typical scope of services that a CPL is expected to perform, including product testing services, and discusses the basic principles behind the most frequent procedures. Quality management (QM) principles specific to a CPL are also discussed. References to additional guidance documents that are available worldwide to assist with QM and regulatory compliance are also provided.
Author List
Leemhuis T, Padley D, Keever-Taylor C, Niederwieser D, Teshima T, Lanza F, Chabannon C, Szabolcs P, Bazarbachi A, Koh MB, Graft Processing Subcommittee of the Worldwide Network for Blood and Bone Marrow Transplantation (WBMT)MESH terms used to index this publication - Major topics in bold
Hematopoietic Stem Cell TransplantationHematopoietic Stem Cells
Humans
Laboratories, Hospital
Medical Laboratory Personnel
Practice Guidelines as Topic