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Review of the use of lipid emulsion in nonlocal anesthetic poisoning. Pediatr Emerg Care 2014 Jun;30(6):427-33; quiz 434-6

Date

06/04/2014

Pubmed ID

24892685

DOI

10.1097/PEC.0000000000000155

Scopus ID

2-s2.0-84902515214 (requires institutional sign-in at Scopus site)   7 Citations

Abstract

Intravenous lipid emulsion (ILE) has been used widely for the treatment of poisoning due to local anesthetic agent and is increasingly reported as a therapy for other forms of poisoning. This article will review the proposed mechanisms of action for ILE in poisoning and the evidence from animal studies and human experience supporting the use of ILE for poisoning due to nonlocal anesthetic agents.

Author List

Kostic MA, Gorelick M

Author

Mark Kostic MD Professor in the Emergency Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Anesthetics, Local
Animals
Antidotes
Fat Emulsions, Intravenous
Humans
Lipids