Medical College of Wisconsin
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Exchange blood transfusion compared with simple transfusion for first overt stroke is associated with a lower risk of subsequent stroke: a retrospective cohort study of 137 children with sickle cell anemia. J Pediatr 2006 Nov;149(5):710-2 PMID: 17095350

Pubmed ID

17095350

Abstract

A retrospective cohort study of children with sickle cell anemia (SCA) and strokes was used to test the hypothesis that exchange transfusion at the time of stroke presentation more effectively prevents second strokes than does simple transfusion. Children receiving simple transfusion had a 5-fold greater relative risk (95% confidence interval = 1.3 to 18.6) of second stroke than those receiving exchange transfusion.

Author List

Hulbert ML, Scothorn DJ, Panepinto JA, Scott JP, Buchanan GR, Sarnaik S, Fallon R, Chu JY, Wang W, Casella JF, Resar L, Berman B, Adamkiewicz T, Hsu LL, Smith-Whitley K, Mahoney D, Woods G, Watanabe M, DeBaun MR

Authors

Julie A. Panepinto MD, MSPH Professor in the Pediatrics department at Medical College of Wisconsin
John Paul Scott MD Professor in the Pediatrics department at Medical College of Wisconsin




Scopus

2-s2.0-33750614993   78 Citations

MESH terms used to index this publication - Major topics in bold

Adolescent
Anemia, Sickle Cell
Blood Transfusion
Child
Child, Preschool
Disease-Free Survival
Exchange Transfusion, Whole Blood
Female
Follow-Up Studies
Humans
Infant
Male
Recurrence
Retrospective Studies
Risk Assessment
Risk Factors
Stroke
Time Factors
jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad