Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Turnover of mouse photoreceptor outer segments in constant light and darkness. Invest Ophthalmol Vis Sci 1979 Oct;18(10):1019-24 PMID: 478775

Pubmed ID

478775

Abstract

Pigmented mice differ from frogs in that lighting regime has only a small effect on rod outer segment turnover. During 8 days in constant light or darkness, disc addition measured as total displacement of a radioactive band in rod outer segments of mice which has received injections of tritiated amino acids was never modified by more than 7% compared to cyclic light controls. Disc shedding continued in each lighting regime, and as judged from outer segment dimensions, disc shedding approximately balanced disc addition.

Author List

Besharse JC, Hollyfield JG

Author

Joseph C. Besharse PhD Director, Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin




Scopus

2-s2.0-0018306891   67 Citations

MESH terms used to index this publication - Major topics in bold

Animals
Autoradiography
Darkness
Leucine
Light
Male
Mice
Mice, Inbred C57BL
Optic Disk
Phagocytes
Phenylalanine
Photic Stimulation
Photoreceptor Cells
Tritium
jenkins-FCD Prod-353 9ccd8489072cb19f5b9f808bb23ed672c582f41e