Medical College of Wisconsin
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Prostate pointers and pitfalls: the 10 most prevalent problems in prostate biopsy interpretation. Ann Diagn Pathol 2014 Oct;18(5):301-11

Date

08/17/2014

Pubmed ID

25128443

DOI

10.1016/j.anndiagpath.2014.07.003

Scopus ID

2-s2.0-84908234124   3 Citations

Abstract

As small volumes of prostate cancer are being detected with ever-increasing frequency, the pathologist is challenged to make more diagnostically out of less. This photoessay explores ten diagnostic problems that are noted with regularity by a provider of second opinions in prostate biopsy interpretation. These include: suboptimal submission of prostate cores, atypia with small size of the focus of concern, cytologic ambiguity of the focus of concern, issues with ordering and interpreting immunostains, atypia arising with high-grade prostatic intraepithelial neoplasia, benign mimics of cancer, omitting mention of extraprostatic tumor extension or of Gleason pattern 5, not recognizing intraductal carcinoma, and the differential diagnosis of cancer of urothelial versus prostatic origin.

Author List

Iczkowski KA

Author

Kenneth A. Iczkowski MD Professor in the Pathology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adenocarcinoma
Biopsy
Humans
Male
Prostatic Neoplasms
jenkins-FCD Prod-400 0f9a74600e4e79798f8fa6f545ea115f3dd948b2