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Neural tube dysraphism: review of cutaneous markers and imaging. Pediatr Dermatol 2015 Mar-Apr;32(2):161-70 PMID: 25557454

Pubmed ID

25557454

Abstract

Neural tube dysraphisms are congenital anomalies resulting from impaired formation of structures along the craniospinal axis during central nervous system development. When these malformations are large or lack a skin covering, they are easily recognized, whereas smaller or skin-covered malformations may not be readily apparent. Due to the intimate embryologic origin of the skin and nervous system, these occult malformations are often heralded by associated cutaneous abnormalities. In this article, the common clinical presentations and cutaneous markers of craniospinal dysraphism are reviewed, along with the recommended imaging modalities.

Author List

Sewell MJ, Chiu YE, Drolet BA

Authors

Yvonne E. Chiu MD Associate Professor in the Dermatology department at Medical College of Wisconsin
Beth A. Drolet MD Professor in the Dermatology department at Medical College of Wisconsin




Scopus

2-s2.0-84925374007   12 Citations

MESH terms used to index this publication - Major topics in bold

Biomarkers
Dermoid Cyst
Encephalocele
Female
Humans
Infant, Newborn
Male
Meningocele
Neural Tube
Neural Tube Defects
Prevalence
Prognosis
Risk Assessment
Skin Abnormalities
Spinal Dysraphism
jenkins-FCD Prod-300 626508253d14e4184314fb9f66322a03a5906796