Neural tube dysraphism: review of cutaneous markers and imaging. Pediatr Dermatol 2015;32(2):161-70
Date
01/06/2015Pubmed ID
25557454DOI
10.1111/pde.12485Scopus ID
2-s2.0-84925374007 (requires institutional sign-in at Scopus site) 47 CitationsAbstract
Neural tube dysraphisms are congenital anomalies resulting from impaired formation of structures along the craniospinal axis during central nervous system development. When these malformations are large or lack a skin covering, they are easily recognized, whereas smaller or skin-covered malformations may not be readily apparent. Due to the intimate embryologic origin of the skin and nervous system, these occult malformations are often heralded by associated cutaneous abnormalities. In this article, the common clinical presentations and cutaneous markers of craniospinal dysraphism are reviewed, along with the recommended imaging modalities.
Author List
Sewell MJ, Chiu YE, Drolet BAAuthor
Yvonne E. Chiu MD Vice Chair, Professor in the Dermatology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
BiomarkersDermoid Cyst
Encephalocele
Female
Humans
Infant, Newborn
Male
Meningocele
Neural Tube
Neural Tube Defects
Prevalence
Prognosis
Risk Assessment
Skin Abnormalities
Spinal Dysraphism
