Faculty Collaboration Database

Assessment of an innovative antimicrobial surface disinfectant in the operating room environment using adenosine triphosphate bioluminescence assay. Am J Infect Control 2015 Mar 01;43(3):283-5

Date

03/03/2015

Pubmed ID

25728155

DOI

10.1016/j.ajic.2014.11.023

Scopus ID

2-s2.0-84923547824 (requires institutional sign-in at Scopus site)   15 Citations

Abstract

Terminal cleaning in the operating room is a critical step in preventing the transmission of health care-associated pathogens. The persistent disinfectant activity of a novel isopropyl alcohol/organofunctional silane solution (ISO) was evaluated in 4 operating rooms after terminal cleaning. Adenosine triphosphate bioluminescence documented a significant difference (P < .048) in surface bioburden on IOS-treated surfaces versus controls. RODAC plate cultures revealed a significant (P < .001) reduction in microbial contamination on IOS-treated surfaces compared with controls. Further studies are warranted to validate the persistent disinfectant activity of ISO within selective health care settings.

Author List

Lewis BD, Spencer M, Rossi PJ, Lee CJ, Brown KR, Malinowski M, Seabrook GR, Edmiston CE Jr

Authors

Brian D. Lewis MD Professor in the Surgery department at Medical College of Wisconsin
Michael Malinowski MD Associate Professor in the Surgery department at Medical College of Wisconsin
Peter J. Rossi MD Chief, Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

2-Propanol
Adenosine Triphosphate
Disinfectants
Environmental Microbiology
Health Services Research
Humans
Infection Control
Luminescent Measurements
Operating Rooms
Silanes