Effects of radiation upon gastrointestinal motility. World J Gastroenterol 2007 May 21;13(19):2684-92
Date
06/15/2007Pubmed ID
17569136Pubmed Central ID
PMC4147116DOI
10.3748/wjg.v13.i19.2684Scopus ID
2-s2.0-34250772243 (requires institutional sign-in at Scopus site) 25 CitationsAbstract
Whether due to therapeutic or belligerent exposure, the gastrointestinal effects of irradiation produce symptoms dreaded by a majority of the population. Nausea, vomiting, diarrhea and abdominal cramping are hallmarks of the prodromal phase of radiation sickness, occurring hours to days following radiation exposure. The prodromal phase is distinct from acute radiation sickness in that the absorptive, secretory and anatomic changes associated with radiation damage are not easily identifiable. It is during this phase of radiation sickness that gastrointestinal motility significantly changes. In addition, there is evidence that motor activity of the gut contributes to some of the acute and chronic effects of radiation.
Author List
Otterson MFAuthor
Mary F. Otterson MD Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Anal CanalGastrointestinal Motility
Humans
Muscle Contraction
Muscle, Smooth
Radiation Injuries
Rectum