Gallium citrate Ga 67 scanning: clinical usefulness in lymphoma patients. Arch Intern Med 1976 Dec;136(12):1370-4
Date
12/01/1976Pubmed ID
793551Scopus ID
2-s2.0-84942484277 (requires institutional sign-in at Scopus site) 25 CitationsAbstract
Gallium citrate Ga 67 (67Ga) scans were performed in 50 consecutive lymphoma patients who underwent routine staging. The overall accuracy of 67Ga scans was greater than 80% for all nodal sites except the spleen (68%). Sensitivity was greater than 88% in the neck and mediastinum, 67% in the abdomen-pelvis, and 33% for the spleen. Specificity was greater than 85% for all nodal sites except for the mediastinum (67%). The accuracy of pedal lymphangiograms was 75%, sensitivity 87%, and specificity 68%. Gallium 67 scans complemented the lymphogram in the abdomen-pelvis but, due to limited sensitivity and high number of equivocal studies (16%), did not replace it. Infraclavicular, pectoral, and mediastinal lesions were detected by 67Ga scans when missed by other means. In 20% to 25% of patients, 67Ga scans provided information not afforded by other diagnostic studies and are therefore considered an important staging procedure for lymphoma patients.
Author List
Seabold JE, Votaw ML, Keyes JW Jr, Foley WD, Balachandran S, Gill SPMESH terms used to index this publication - Major topics in bold
Abdominal NeoplasmsAdolescent
Adult
Female
Gallium Radioisotopes
Hodgkin Disease
Humans
Lymphography
Lymphoma
Lymphoma, Large B-Cell, Diffuse
Lymphoma, Non-Hodgkin
Male
Mediastinal Neoplasms
Middle Aged
Pelvic Neoplasms
Radionuclide Imaging