Faculty Collaboration Database

Ultrahigh density microarrays of solid samples. Nat Methods 2005 Jul;2(7):511-3

Date

06/24/2005

Pubmed ID

15973421

DOI

10.1038/nmeth772

Scopus ID

2-s2.0-23644452105 (requires institutional sign-in at Scopus site)   34 Citations

Abstract

We present a sectioning and bonding technology to make ultrahigh density microarrays of solid samples, cutting edge matrix assembly (CEMA). Maximized array density is achieved by a scaffold-free, self-supporting construction with rectangular array features that are incrementally scalable. This platform technology facilitates arrays of >10,000 tissue features on a standard glass slide, inclusion of unique sample identifiers for improved manual or automated tracking, and oriented arraying of stratified or polarized samples.

Author List

LeBaron MJ, Crismon HR, Utama FE, Neilson LM, Sultan AS, Johnson KJ, Andersson EC, Rui H

MESH terms used to index this publication - Major topics in bold

Equipment Design
Equipment Failure Analysis
Microarray Analysis
Microtomy
Specimen Handling
Tissue Culture Techniques
Tissue Embedding