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Antibiotic sensitivity and resistance patterns in pediatric staphylococcal scalded skin syndrome. Pediatr Dermatol 2014 May-Jun;31(3):305-8 PMID: 24033633 PMCID: PMC4349361

Pubmed ID

24033633

DOI

10.1111/pde.12195

Abstract

Historical resistance patterns often guide empiric antibiotic choices in staphylococcal scalded skin syndrome (SSSS), but little is known about the difference in susceptibility between SSSS and other childhood staphylococcal infections. A retrospective chart review of culture-confirmed cases of SSSS seen in the inpatient dermatology consultation service at the Children's Hospital of Philadelphia between 2005 and 2011 was performed. Most cases of SSSS at our institution are due to oxacillin-susceptible Staphylococcus aureus, and approximately half of the cases are due to clindamycin-resistant strains. Clindamycin and a penicillinase-resistant penicillin are suggested as empiric treatment for SSSS until culture susceptibility data are available to guide therapy.

Author List

Braunstein I, Wanat KA, Abuabara K, McGowan KL, Yan AC, Treat JR

Author

Karolyn A. Wanat MD Associate Professor in the Dermatology department at Medical College of Wisconsin




Scopus

2-s2.0-84899503143   14 Citations

MESH terms used to index this publication - Major topics in bold

Anti-Bacterial Agents
Child, Preschool
Clindamycin
Drug Resistance, Bacterial
Female
Hospitals, Pediatric
Humans
Infant
Male
Oxacillin
Penicillinase
Philadelphia
Retrospective Studies
Staphylococcal Scalded Skin Syndrome
Staphylococcus aureus
jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad