Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Neonatal outcomes in twin pregnancies complicated by gestational diabetes compared with non-diabetic twins. J Perinatol 2015 Dec;35(12):1043-7 PMID: 26513454

Pubmed ID

26513454

Abstract

OBJECTIVE: To compare neonatal outcomes of twin pregnancies with gestational diabetes (GDM) and preexisting diabetes with non-diabetic twin pregnancies.

STUDY DESIGN: US birth data from 2006 to 2009 was used to compare twin pregnancies of 16 562 GDM and 2137 preexisting diabetic with 258 857 non-diabetic twin gestations. Adjusted odds ratios (aORs) were calculated to assess effects of GDM and preexisting diabetes on neonatal outcomes.

RESULT: Twin pregnancies with GDM vs non-diabetic twin pregnancies demonstrated decreased 5-min Apgar scores <4 (aOR 0.8, 95% confidence interval (CI) 0.68-0.94), fewer births before 32 weeks gestation (aOR 0.72, 95% CI 0.68-0.76), decreased birth weight less than the tenth percentile (aOR 0.84, 95% CI 0.81-0.89) and fifth percentile (aOR 0.85, 95% CI 0.81-0.89) and a trend toward lower rates of neonatal death (aOR 0.84, 95% CI 0.68-1.02).

CONCLUSION: Certain adverse outcomes in pregnancies with GDM may be attenuated in twin gestations; however, further investigation is warranted.

Author List

Foeller ME, Zhao S, Szabo A, Cruz MO

Authors

Meredith Cruz MD Assistant Professor in the Obstetrics and Gynecology department at Medical College of Wisconsin
Aniko Szabo PhD Associate Professor in the Institute for Health and Equity department at Medical College of Wisconsin




Scopus

2-s2.0-84948082121   5 Citations

MESH terms used to index this publication - Major topics in bold

Adult
Apgar Score
Diabetes, Gestational
Female
Gestational Age
Humans
Infant, Newborn
Perinatal Death
Pregnancy
Pregnancy Complications
Pregnancy in Diabetics
Pregnancy, Twin
Retrospective Studies
Young Adult
jenkins-FCD Prod-299 9ef562391eceb2b8f95265c767fbba1ce5a52fd6