Faculty Collaboration Database

Postoperative Complications in the Ahmed Baerveldt Comparison Study During Five Years of Follow-up. Am J Ophthalmol 2016 Mar;163:75-82.e3

Date

11/26/2015

Pubmed ID

26596400

Pubmed Central ID

PMC4901387

DOI

10.1016/j.ajo.2015.11.023

Scopus ID

2-s2.0-84959396066 (requires institutional sign-in at Scopus site)   127 Citations

Abstract

PURPOSE: To compare the late complications in the Ahmed Baerveldt Comparison Study during 5 years of follow-up.

DESIGN: Multicenter, prospective randomized clinical trial.

METHODS: setting: Sixteen international clinical centers.

STUDY POPULATION: Two hundred seventy-six subjects aged 18-85 years with previous intraocular surgery or refractory glaucoma with intraocular pressure of >18 mm Hg.

INTERVENTIONS: Ahmed Glaucoma Valve FP7 or Baerveldt Glaucoma Implant BG 101-350.

MAIN OUTCOME MEASURES: Late postoperative complications (beyond 3 months), reoperations for complications, and decreased vision from complications.

RESULTS: Late complications developed in 56 subjects (46.8 ± 4.8 5-year cumulative % ± SE) in the Ahmed Glaucoma Valve group and 67 (56.3 ± 4.7 5-year cumulative % ± SE) in the Baerveldt Glaucoma Implant group (P = .082). The cumulative rates of serious complications were 15.9% and 24.7% in the Ahmed Glaucoma Valve and Baerveldt Glaucoma Implant groups, respectively (P = .034), although this was largely driven by subjects who had tube occlusions in the 2 groups (0.8% in the Ahmed Glaucoma Valve group and 5.7% in the Baerveldt Glaucoma Implant group, P = .037). Both groups had a relatively high incidence of persistent diplopia (12%) and corneal edema (20%), although half of the corneal edema cases were likely due to pre-existing causes other than the aqueous shunt. The incidence of tube erosion was 1% and 3% in the Ahmed Glaucoma Valve and Baerveldt Glaucoma Implant groups, respectively (P = .04).

CONCLUSIONS: Long-term rates of vision-threatening complications and complications resulting in reoperation were higher in the Baerveldt Glaucoma Implant than in the Ahmed Glaucoma Valve group over 5 years of follow-up.

Author List

Budenz DL, Feuer WJ, Barton K, Schiffman J, Costa VP, Godfrey DG, Buys YM, Ahmed Baerveldt Comparison Study Group

MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Aged
Aged, 80 and over
Female
Follow-Up Studies
Glaucoma Drainage Implants
Glaucoma, Open-Angle
Humans
Intraocular Pressure
Male
Middle Aged
Postoperative Complications
Prospective Studies
Prosthesis Implantation
Reoperation
Time Factors
Tonometry, Ocular
Visual Acuity