Medical College of Wisconsin
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Hemodynamics of vein graft stenosis. J Vasc Surg 1988 Dec;8(6):688-95



Pubmed ID




Scopus ID

2-s2.0-0024245660   61 Citations


The hemodynamics of 56 femorodistal saphenous vein bypasses (in situ [n = 53] or reversed [n = 3]) identified to have residual or recurrent graft stenoses were characterized with Doppler-derived blood flow velocity and resting limb systolic pressure measurements. The magnitude and configuration of the graft blood flow velocity waveform were the best predictors of graft stenosis. Transformation of the graft blood flow velocity waveform from a triphasic to a monophasic or biphasic configuration coupled with a low (less than 45 cm/sec) or decrease (greater than 30 cm/sec) in peak systolic blood flow velocity relative to initial postoperative levels reliably predicted the presence of a remote occlusive lesion. In 20 (36%) of the 56 limbs, the ankle-brachial systolic pressure index (ABI) did not identify graft stenosis. The low sensitivity of ABI in the identification of graft stenosis was due to insignificant decrease (less than 0.15) of ABI (n = 11), incompressibility of the tibial arteries (n = 6), or residual occlusive lesions after surgery (n = 3). Duplex scanning of grafts with low blood flow velocity localized the site of stenosis in 31 (86%) of 36 patients examined. Graft revision increased systolic blood flow velocity from 33 +/- 9 to 77 +/- 18 cm/sec (mean +/- one standard deviation) a velocity similar to immediate postoperative levels (74 +/- 17 cm/sec). Resting ABI increased from 0.61 +/- 0.2 to 0.92 +/- 0.1 after graft revision. Four grafts with low systolic blood flow velocity (range 18 to 40 cm/sec) not revised occluded 5 to 45 days later.(ABSTRACT TRUNCATED AT 250 WORDS)

Author List

Bandyk DF, Seabrook GR, Moldenhauer P, Lavin J, Edwards J, Cato R, Towne JB


Gary R. Seabrook MD Chief, Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Blood Flow Velocity
Constriction, Pathologic
Femoral Vein
Graft Occlusion, Vascular
Middle Aged
Saphenous Vein
Vascular Patency
jenkins-FCD Prod-468 69a93cef3257f26b866d455c1d2b2d0f28382f14