Faculty Collaboration Database

Central nervous system lesions in pediatric patients: Gd-DTPA-enhanced MR imaging. Radiology 1988 Dec;169(3):723-6

Date

12/01/1988

Pubmed ID

3055036

DOI

10.1148/radiology.169.3.3055036

Scopus ID

2-s2.0-0023769888 (requires institutional sign-in at Scopus site)   36 Citations

Abstract

Twenty pediatric patients, aged 2-18 years, with known or suspected masses in the brain and/or spinal cord were studied with magnetic resonance imaging at 0.6T with and without use of 0.1 mmol/kg gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA). The multisection, multiecho imaging mode was utilized. Surgically proved mass lesions included astrocytoma (n = 6), medulloblastoma (n = 2), ependymoma (n = 1), craniopharyngioma (n = 1), oligodendroglioma (n = 1), germinoma (n = 1) and fibrosarcoma (n = 1). Presumptive diagnoses included astrocytoma (n = 3), arachnoid cyst (n = 1), tuberous sclerosis (n = 1), cryptic vascular malformation (n = 1), and normal (n = 1). There was dramatic enhancement in 11 of 20 patients, with improved definition of the presence and extent of lesions in six patients. No adverse effects were noted in any of the 20 patients. It is concluded that Gd-DTPA is useful in delineating the presence, extent, and number of certain lesions of the central nervous system in children.

Author List

Powers TA, Partain CL, Kessler RM, Freeman MW, Robertson RH, Wyatt SH, Whelan HT

MESH terms used to index this publication - Major topics in bold

Adolescent
Astrocytoma
Brain Neoplasms
Central Nervous System Diseases
Child
Child, Preschool
Contrast Media
Female
Gadolinium
Gadolinium DTPA
Humans
Magnetic Resonance Imaging
Male
Medulloblastoma
Multicenter Studies as Topic
Organometallic Compounds
Pentetic Acid