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Metaplastic breast cancer: histologic characteristics, prognostic factors and systemic treatment strategies. Exp Hematol Oncol 2013 Nov 14;2(1):31

Date

02/07/2014

Pubmed ID

24499560

Pubmed Central ID

PMC3832232

DOI

10.1186/2162-3619-2-31

Abstract

Metaplastic breast cancer (MBC) is a rare subtype of invasive breast cancer that tends to have an aggressive clinical presentation as well as a variety of distinct histologic designations. Few systemic treatment options are available for MBC, as it has consistently shown a suboptimal response to standard chemotherapy regimens. These characteristics result in a worse overall prognosis for patients with MBC compared to those with standard invasive breast cancer. Due to its rarity, data focusing on MBC is limited. This review will discuss the clinical presentation, breast imaging findings, histologic and molecular characteristics of MBC as well as potential future research directions.

Author List

Schwartz TL, Mogal H, Papageorgiou C, Veerapong J, Hsueh EC

Author

Harveshp Mogal MD Assistant Professor in the Surgery department at Medical College of Wisconsin




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