New concepts in the pathogenesis and treatment of allergic asthma. Mt Sinai J Med 1998 Sep;65(4):246-56
Date
10/03/1998Pubmed ID
9757744Scopus ID
2-s2.0-0031687884 (requires institutional sign-in at Scopus site) 3 CitationsAbstract
This review delineates the currently accepted, multifaceted approach to the care of an asthmatic patient. Therapy is based on our improved understanding of the pathophysiology of this complex disease, in which IgE and mediators derived from many cells contribute to airway inflammation. The latest trends in therapy involve the institution of anti-inflammatory medications relatively early in disease. With the recent availability of a novel class of therapies, the leukotriene antagonists, and other therapies based on antagonism of adhesion molecules, cytokines, chemokines, or IgE itself, the future may provide additional alternatives for the physician treating patients with asthma.
Author List
Grayson MH, Bochner BSMESH terms used to index this publication - Major topics in bold
Anti-Asthmatic AgentsApoptosis
Asthma
Cell Adhesion Molecules
Cytokines
Humans
Immunoglobulin E