Eczema and Urticaria as Manifestations of Undiagnosed and Rare Diseases. Pediatr Clin North Am 2017 Feb;64(1):39-56
Date
11/30/2016Pubmed ID
27894451DOI
10.1016/j.pcl.2016.08.004Scopus ID
2-s2.0-84998787314 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
Eczema and urticaria are common disorders encountered in pediatric patients, but they may occasionally be the presenting complaint in a child with an underlying rare disease. Immunodeficiency syndromes should be suspected when eczema is associated with neonatal onset, recurrent infections, chronic lymphadenopathy, or failure to thrive. Nutritional deficiencies and mycosis fungoides are in the differential diagnosis for a child with a recalcitrant eczematous eruption. Autoinflammatory syndromes should be suspected in a child with chronic urticaria, fever, and other systemic signs of inflammation. Although these disorders are rare, early recognition allows for appropriate treatment and decreased morbidity for the child.
Author List
Youssef MJ, Chiu YEAuthor
Yvonne E. Chiu MD Vice Chair, Professor in the Dermatology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
ChildChild Nutrition Disorders
Diagnosis, Differential
Eczema
Hereditary Autoinflammatory Diseases
Humans
Immunologic Deficiency Syndromes
Mycosis Fungoides
Rare Diseases
Urticaria
