Faculty Collaboration Database

The additive value of three-dimensional derived left atrial volume and carotid imaging in dobutamine stress echocardiography. Eur J Echocardiogr 2011 Jan;12(1):46-53

Date

09/11/2010

Pubmed ID

20829208

DOI

10.1093/ejechocard/jeq104

Scopus ID

2-s2.0-78651357800 (requires institutional sign-in at Scopus site)   2 Citations

Abstract

AIMS: to evaluate whether the three-dimensional (3D) left atrial volume index (LAVI) and/or the presence of carotid plaques (CP) can predict the result of dobutamine stress echocardiography (DSE), thereby aiding interpretation.

METHODS AND RESULTS: we studied 130 patients (52 male, mean age 63 ± 11 years) with normal resting wall motion (WM) undergoing DSE. All patients had the end-systolic 2D and 3D LAVI measured, as well as bilateral carotid scanning. DSE was reported as abnormal in 50 (38.5%) patients. 3D end-systolic LAVI measurements were significantly higher (31.5 ± 8.2 vs 27.4 ± 7.4 mL/m(2), P = 0.004) in those with an abnormal DSE. The two groups did not differ significantly on the 2D derived maximum LAVI measurements (36.2 ± 9.5 vs 34.2 ± 11.2, P = 0.299) and the presence of plaques in the carotid arteries (89.1 vs. 76.2%, P = 0.100). Receiver operating characteristic curves were created to define cut-offs that could predict the DSE result for the 3D LAVI. A 3D LAVI of >24.5 mL/m(2) had a sensitivity of 80% for predicting an abnormal DSE, whereas a value of >36.0 mL/m(2) had a specificity of 93% for the same cause. Intra-observer (r = 0.997, P < 0.0001) and inter-observer (r = 0.961, P < 0.0001) variability for 3D LAVI measurements was found to be excellent.

CONCLUSION: three-dimensional (but not 2D) assessment of LAVI may offer additional information in predicting the result of DSE. Carotid scanning did not offer additional information for the same cause.

Author List

Sachpekidis V, Bhan A, Paul M, Gianstefani S, Smith L, Reiken J, Walker N, Harries D, Pearson P, Monaghan MJ

Author

Paul Joseph Pearson MD, PhD Chief, Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Aged
Aged, 80 and over
Chest Pain
Chi-Square Distribution
Coronary Artery Disease
Echocardiography, Stress
Echocardiography, Three-Dimensional
Female
Heart Atria
Humans
Male
Middle Aged
Prospective Studies
ROC Curve
Sensitivity and Specificity