Faculty Collaboration Database

Chelate-Assisted Oxidative Coupling Reaction of Arylamides and Unactivated Alkenes: Mechanistic Evidence for Vinyl C-H Bond Activation Promoted by an Electrophilic Ruthenium-Hydride Catalyst. Organometallics 2010 Oct 21;29(22):5748-5750

Date

02/24/2011

Pubmed ID

21344062

Pubmed Central ID

PMC3041965

DOI

10.1021/om100764c

Scopus ID

2-s2.0-78649293177 (requires institutional sign-in at Scopus site)   81 Citations

Abstract

The cationic ruthenium-hydride complex [(η(6)-C(6)H(6))(PCy(3))(CO)RuH](+)BF(4) (-) was found to be a highly regioselective catalyst for the oxidative C-H coupling reaction of aryl-substituted amides and unactivated alkenes to give ortho-alkenylamide products. The kinetic and spectroscopic analyses support a mechanism involving a rapid vinyl C-H activation followed by a rate-limiting C-C bond formation steps.

Author List

Kwon KH, Lee DW, Yi CS

Author

Chae Yi PhD Professor, Inorganic and Organometallic Chemistry, Homogeneous Catalysis in the Chemistry department at Marquette University