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Aqueous phase C-H bond oxidation reaction of arylalkanes catalyzed by a water-soluble cationic Ru(III) complex [(pymox-Me2)2RuCl2]+BF4-. Org Lett 2009 Apr 02;11(7):1567-9

Date

02/28/2009

Pubmed ID

19245262

Pubmed Central ID

PMC2667693

DOI

10.1021/ol900097y

Abstract

The cationic complex [(pymox-Me(2))RuCl(2)](+)BF(4)(-) was found to be a highly effective catalyst for the C-H bond oxidation reaction of arylalkanes in water. For example, the treatment of ethylbenzene (1.0 mmol) with t-BuOOH (3.0 mmol) and 1.0 mol % of the Ru catalyst in water (3 mL) cleanly produced PhCOCH(3) at room temperature. Both a large kinetic isotope effect (k(H)/k(D) = 14) and a relatively large Hammett value (rho = -1.1) suggest a solvent-caged oxygen rebounding mechanism via a Ru(IV)-oxo intermediate species.

Author List

Yi CS, Kwon KH, Lee DW

Author

Chae Yi PhD Professor, Inorganic and Organometallic Chemistry, Homogeneous Catalysis in the Chemistry department at Marquette University




MESH terms used to index this publication - Major topics in bold

Alkanes
Catalysis
Combinatorial Chemistry Techniques
Kinetics
Molecular Structure
Organometallic Compounds
Oxidation-Reduction
Ruthenium
Water
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