Regulating the regulator of ROS production. Cell Res 2014 Aug;24(8):908-9
Date
05/21/2014Pubmed ID
24839902Pubmed Central ID
PMC4123290DOI
10.1038/cr.2014.66Scopus ID
2-s2.0-84905591141 (requires institutional sign-in at Scopus site) 12 CitationsAbstract
Balancing inflammatory reactive oxygen species (ROS) production is essential for safely eliminating pathogenic microbes. The newly described protein Negative Regulator of ROS (NRROS) dampens ROS production by restricting NOX2 availability, and thus "cools-off" inflammation.
Author List
Bonini MG, Malik ABMESH terms used to index this publication - Major topics in bold
AnimalsEncephalomyelitis, Autoimmune, Experimental
Escherichia coli
Female
Listeria monocytogenes
Male
Proteins
Reactive Oxygen Species
