The epidemiology of human papillomaviruses. Curr Probl Dermatol 2014;45:75-91
Date
03/20/2014Pubmed ID
24643179DOI
10.1159/000358370Scopus ID
2-s2.0-84905462033 (requires institutional sign-in at Scopus site) 23 CitationsAbstract
Epidemiological studies indicate that most men and women will acquire a sexually transmitted anogenital human papillomavirus (HPV) infection in their lifetimes. In addition, infection with cutaneous HPV types is essentially ubiquitous. Most HPV infections are transient with no clinical symptoms although a minority of infections result in clinical disease such as warts or malignancies. Anogenital warts are the most common clinical manifestation of HPV infection with a prevalence of perhaps 1%. Virtually 100% of cervical cancers, 90-93% of anal canal cancers, 12-63% of oropharyngeal cancers, 36-40% of penile cancers, 40-64% of vaginal cancers and 40-51% of vulvar cancers are attributable to HPV infection. Of the estimated 12.7 million cancers occurring globally in 2008, 610,000 (approx. 5%) were HPV-associated anogenital or oral cancers. Cutaneous HPV types may increase the risk for nonmelanoma skin cancers. Sexual behavior is a primary risk factor associated with anogenital and oral HPV infection among men and women.
Author List
Nyitray AG, Iannacone MRAuthor
Alan Nyitray PhD Associate Professor in the Psychiatry and Behavioral Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
FemaleHumans
Male
Papillomavirus Infections
Risk Factors
Sexually Transmitted Diseases, Viral
Skin Diseases, Viral
Urogenital Neoplasms