Medical College of Wisconsin
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Extensive carcinoma cuniculatum of the mandible. Am J Otolaryngol 2015 May-Jun;36(3):446-50 PMID: 25659461

Pubmed ID



Carcinoma cuniculatum (CC) is a rare variant of squamous cell carcinoma first described in 1954. Cases of CC in the head and neck are exceedingly rare, with 66 cases reported since 1977. These tumors are generally low-grade, well-differentiated and locally aggressive malignancies. Patients are often subjected to a long period of misdiagnoses given the clinical similarity of these entities to odontogenic cysts and abscesses. We report a case of a carcinoma cuniculatum of the mandible with very advanced local involvement of disease, highlighting the unusual characteristics of this rare tumor that are important for clinicians to recognize. Clinical presentation, histology, risk factors, treatment options, and prognosis are also reviewed.

Author List

Shay S, Choy W, Christensen RE, St John MA


Sophie G. Shay MD Assistant Professor in the Otolaryngology department at Medical College of Wisconsin


2-s2.0-84929026727   2 Citations

MESH terms used to index this publication - Major topics in bold

Carcinoma, Squamous Cell
Mandibular Neoplasms
Middle Aged
jenkins-FCD Prod-271 16cb5dcaa6d2cfe4986875aea432578e3ad30554