Motives for joining an unrelated HSC donor registry: description, categorization, and association with donor availability. Bone Marrow Transplant 2019 Mar;54(3):425-431
Date
08/09/2018Pubmed ID
30087465DOI
10.1038/s41409-018-0278-2Scopus ID
2-s2.0-85052526938 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
A challenge for registries of unrelated hematopoietic stem cell (HSC) donors is to recruit and retain sufficient donors for patients needing transplants. Many registered HSC donors opt-out when called as a potential match for a patient. Anecdotal evidence suggests that motives for joining a registry may be linked to the donation decision. The primary goals of this investigation were to describe the range of motives for joining a registry and to examine donor availability by motive type. A diverse sample of 357 potential HSC donors from the Anthony Nolan registry in the UK was asked about their motives for joining and their decision to continue or opt-out after matching a patient was recorded. Motives for joining (N = 557) were first coded and categorized into 17 specific motive types and then arranged along a spectrum from internal to external. Internal values-based motives were most prevalent and availability was highest among potential donors expressing these motives (92%) and lowest among those expressing external motives (pressure, incentives; 0%). Although further research is needed to confirm these findings, they suggest that registries should assess donors' motives for joining at recruitment in order to conduct follow-up to ensure commitment among those potential members expressing external motives.
Author List
La Casta AH, Shaw BE, Anthias C, Bruce JG, Pastorek G, Billen A, O'Leary A, Switzer GEAuthor
Bronwen E. Shaw MBChB, PhD Center Director, Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultHematopoietic Stem Cell Transplantation
Humans
Registries
Transplantation Conditioning
Unrelated Donors
