Positive 2-Tiered Lyme Disease Serology is Uncommon in Asymptomatic Children Living in Endemic Areas of the United States. Pediatr Infect Dis J 2019 May;38(5):e105-e107
Date
08/02/2018Pubmed ID
30067595Pubmed Central ID
PMC6355375DOI
10.1097/INF.0000000000002157Scopus ID
2-s2.0-85062407421 (requires institutional sign-in at Scopus site) 10 CitationsAbstract
Knowing the frequency of positive Lyme disease serology in children without signs of infection facilitates test interpretation. Of 315 asymptomatic children from Lyme disease endemic regions, 32 had positive or equivocal C6 enzyme-linked immunoassays, but only 5 had positive IgG or IgM supplemental immunoblots (1.6%; 95% confidence interval: 0.7%-3.7%).
Author List
Garro A, Bennett J, Balamuth F, Levas MN, Neville D, Branda JC, Maulden AB, Lantos PM, Nigrovic LE, Pedi Lyme NetAuthor
Michael Levas MD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAntibodies, Bacterial
Asymptomatic Diseases
Borrelia
Child
Child, Preschool
Female
Humans
Immunoenzyme Techniques
Infant
Lyme Disease
Male
Seroepidemiologic Studies
United States
Young Adult