Medical College of Wisconsin
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Early diagnosis of acute postoperative renal transplant rejection by indium-111-labeled platelet scintigraphy. J Nucl Med 1986 Aug;27(8):1266-72

Date

08/01/1986

Pubmed ID

3525780

Scopus ID

2-s2.0-0022868425 (requires institutional sign-in at Scopus site)   7 Citations

Abstract

A prospective evaluation of 111In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined [99mTc]DTPA and [131I]orthoiodohippurate scintigraphy. With a sensitivity of 0.93 and a specificity of 0.95, IPS provided otherwise unavailable diagnostic information. Furthermore, postoperative IPS was a good predictor of long-term allograft survival.

Author List

Tisdale PL, Collier BD, Kauffman HM, Adams MB, Isitman AT, Hellman RS, Hoffmann RG, Rao SA, Joestgen T, Krohn L



MESH terms used to index this publication - Major topics in bold

Acute Disease
Adolescent
Adult
Blood Platelets
Female
Graft Rejection
Humans
Indium
Kidney
Kidney Transplantation
Male
Middle Aged
Postoperative Period
Prospective Studies
Radioisotopes
Radionuclide Imaging